Neuroimmunology investigates the connections between the bodies immune system and nervous system. It is the study of roles in immune responses to maintaining normal brain function and how immune dysregulation can contribute to many neurological disorders.
Antibodies attack proteins that support the optic nerve and spinal cord, leading to blindness and paralysis. NMO is rare condition in which the immune system targets a person’s optic nerve and spinal chord. Without intervention, this damage leads to paralysis and blindness.
It involves inflammation and swelling of the brain, usually as a result of an underlying tumor. AE involves high levels of inflammation in the brain often due to the presence of a tumor. It causes rapid and often unexplained decline in physical and mental wellbeing.
The BBB is a tight-knit array of cells which protects the brain from circulating toxins and pathogens into the bloodstream. Secondly the BBB is still allowing vital nutrients to be delivered to the brain. Protecting the Central Nervous System (CNS)
Immune molecules and cells shape neuronal networks and synaptic plasticity during brain development.
Immune dysregulation can contribute to neurodevelopmental disorders, such as autism spectrum disorders and schizophrenia.
Immunomodulatory therapies are being developed to treat neurodevelopmental and neurodegenerative disorders.
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These are antibodies designed to target specific immune cells or molecules involved in neuroinflammatory processes. Examples include natalizumab and rituximab.
These involve the use of stem cells or immune cells to modulate immune responses and promote tissue repair. These therapies are being studied for the treatment of multiple sclerosis and other neurological disorders.
Advancements in neuroimmunology offer new hope for the treatment and prevention of neurological disorders. The development of targeted immunotherapies and a deeper understanding of immune regulation and neuroinflammatory processes will usher in a new era of personalized medicine with improved outcomes for patients.
Improved outcomes and quality of life for patients with neurological disorders.
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